Computational Challenges for 3D Atomic Structure Determination
of Large Macromolecules using Cryo-TEM.

      Dan C. Marinescu
      Computer Sciences Department
      Purdue University
      West Lafayette, IN 47907
      Email: dcm@cs.purdue.edu

Abstract

Real-time CryoTEM requires algorithms for
automatic particle identification and parallel
algorithms for orientation determination 
and 3D reconstruction. The talk will review 
our results and discuss the current status of 
an infrastructure for a virtual 
laboratory for computational biolgy.


Dan C. Marinescu is Professor of Computer 
Sciences at Purdue University
He is conducting research in parallel and distributed computing,
and  software agents. He was the chief architect of a distributed data
acquisition and analysis system used in nuclear physics,
now he is the PI of an NSF funded Grand Challenge project to
solve large structural biology problems using parallel
and distributed systems and the Director of the Bond
project (http://bond.cs.purdue.edu).